Example image of eyePlorer eyePlorer map for 'Ohio River': Mississippi River Tributary United States Native Americans in the United States Angel Mounds Chiefdom Earthworks Evansville, Indiana Mississippian culture Mound (disambiguation) Arkansas CE History Iroquois Missouri Oklahoma Osage Indian Territory Kentucky Drainage basin U.S. state Southern United States Tennessee River Northwest Territory Slavery in the United States Mason–Dixon Line Delaware Maryland Northern United States Pennsylvania Upland South Virginia West Virginia Humid continental climate Humid subtropical climate Thomas Jefferson Allegheny River Monongahela River Point State Park Allegheny County, Pennsylvania Beaver County, Pennsylvania Chester, West Virginia East Liverpool, Ohio Midland, Pennsylvania Ohio Wheeling, West Virginia Cincinnati Cairo, Illinois Illinois Indiana